Some are nearly the same thing marketed under different brand names.Īll the available heartworm medications on the market are a variation of what is known clinically as a ML (macrocyclic lactone) compound. You should still keep an eye on your pet when introducing new organic products.īear with me for a little pharmaceutical science, which I promise is important and will make sense in the end! It’s simpler to identify medicines by their components. However, dogs can also be sensitive to essential oils – like my friend who is allergic to lavender – so “natural” doesn’t automatically mean “best” for your dog either. This article from Your Dog Advisor gives natural prevention options and explains how to mix your own parasite preventives using essential oils. Unfortunately I have not learned of any natural pest control products as effective as chemical-based ones. I’ll also discuss organic topicals I’ve found somewhat effective as repellents. However, Collies and associated breeds, with or without an MDR1 status (officially the AbCb1 gene), simply have a reputation for being generally sensitive and prone to side effects from parasite preventives. Any dog can be sensitive to a certain substance and should always be monitored for reactions after a new product has been administered. (Some of the links lead to peer-reviewed scientific articles, so have fun with those if you want the bare, dusty facts.)ĭisclaimer: even parasite protection products officially labeled safe – for an MDR1 dog or any dog – should really be designated “safe-ish.” But parasite preventives are chemical compounds – some of which are used in pesticides – and thus have more potential to cause a reaction than just, well, water. Or check the 100+ comments below this post!įor those who want more in-depth information, I’ve created embedded links throughout for further reading. If you want to know about a specific product, read the active ingredients on the front of the box and compare to one of the products listed in this article. It’s all based off active ingredients. For instance, Heartgard’s main ingredient is Ivermectin, so any product containing Ivermectin falls under the same category. This is not an exhaustive listing of every product out there, but it will provide tools to identify which meds are related to each other or essentially the same as major brands. Sincere apologies to those who read this article start to finish… But hey, repetition is the key to retention, right? In fact, in full expectation most people will skim, I repeat myself a lot. If you’re hoping for a quick, easy skim and just want to know which pest protections are rated safest and best, I’ll give those first under each category. ( Follow this link for official problem drugs.) Technically, they’re all supposed to be safe, but some products are undoubtedly better and more consumer-trusted than others. I’ll list products I’ve looked into – several of which I’ve personally tried – along with whether they’re generally considered safe to use or should be used with caution. I have an Aussie mix, plus three Rough Collies who have 1 copy of the MDR1 gene (carriers/mildly affected), so I have a vested interest in everything I’ve researched. It was somehow both boring and interesting work, but it yielded helpful information. So here’s the culmination of my research: information gathered from laboratory case studies, veterinarians, and Collie owners, breeders, and exhibitors. Available in prescription only.The lack of accessible information on the topic of safe parasite protection for dogs with the MDR1 gene (Multidrug Resistance gene) left me so frustrated that I decided to write my own article. SENTINEL SPECTRUM Chews are indicated for the prevention of heartworm disease caused by Dirofilaria immitis for the prevention and control of flea populations ( Ctenocephalides felis) and for the treatment and control of adult roundworm ( Toxocara canis, Toxascaris leonina), adult hookworm ( Ancylostoma caninum), adult whipworm ( Trichuris vulpis), and adult tapeworm ( Dipylidium caninum, Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus) infections in dogs and puppies two pounds of body weight or greater and six weeks of age and older. In a field study of 117 dogs, greater than 99% accepted the SENTINEL SPECTRUM CHEWS. 1 SENTINEL SPECTRUM Chews has also been shown to be safe for puppies as young as 6 weeks of age, as demonstrated by a second study. All clinical signs resolved within 24 hours. In a margin of safety study, 40 ten-week-old puppies (10 per group) were administered either a placebo or doses of 1, 3, or 5X the maximum exposure dose of SENTINEL SPECTRUM Chews once every 2 weeks for a total of 7 treatments.
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